New Ozempic Side Effect Sparks Growing Concern Among Users
You've probably seen those incredible Ozempic (semaglutide) before-and-after photos flooding your social media feeds. People are losing weight fast with serious transformations. But there's something nobody's talking about in those posts. While the pounds are melting off their bodies, something else is happening to their faces. And it's not what you'd expect. Doctors are calling it “ Ozempic mouth, ” and it’s aging people’s smiles faster than you’d think.
What Doctors Are Seeing (And It's Not Good)
Dr. Michele Green says she sees this daily in her New York practice and it's not just one or two cases, this is becoming her new normal. Patients lose volume in their faces, which creates wrinkles, sagging skin, and droopy areas around their mouths. Deep lines carve into the corners of their mouths while wrinkles mark their lips and loose skin gathers around the chin area, creating hanging skin that wasn't there before. These changes turn bright smiles into aged looks that can make someone appear decades older.
Here's the Real Reason “Ozempic Mouth” Happens
Semaglutide strips away fat from under your skin. When rapid weight loss removes this crucial layer, your skin loses its foundation and begins to collapse forward. Dr. Barry Weintraub, a plastic surgeon in New York, explains that losing this fat makes skin appear thinner and more fragile. This creates those unwanted lines around the mouth that people call “lipstick lines.” Your face essentially deflates, leaving behind loose, wrinkled skin that ages your appearance.
Famous People Show Signs of This Problem
You can look at celebrities like Sharon Osbourne, Rebel Wilson, and Whoopi Goldberg, who've spoken publicly about their use of the medication. These celebrities now show clear signs of these facial changes, and the difference is quite noticeable. The issue affects men just as much. Actor Harvey Fierstein credits Zepbound, another weight loss medication similar to Ozempic, with helping him lose 120 pounds, but his dramatic weight loss also brought loose skin and droopy areas that completely changed his face.
Mouth and Other Body Parts Change with Ozempic
These mouth changes belong to a growing family of body changes that users experience. This problem forms one piece of the larger “Ozempic face ” phenomenon, where rapid weight loss creates sunken cheeks, hollow eyes, and gaunt facial appearances. Users also develop excessively wrinkled and aged-looking feet, while others report bottom deflation and disappearance, making them feel every bone when they sit down. These connected side effects show that the medication reshapes your entire body, not merely your weight.
Millions of People Could Face These Changes
One in eight Americans has tried these injections, though the actual number is likely higher since many people don't report using them due to stigma or use compounded versions that aren't tracked in official statistics. While these injections were originally developed for diabetes treatment, they are now widely prescribed for weight loss, especially among celebrities and public figures. This widespread use explains why cosmetic problems are showing up more often on social media and at celebrity events. With millions of Americans now using these treatments, facial changes could become an increasingly common side effect.
Fixing Your Mouth After Ozempic Comes With a Hefty Price Tag
Dr. Green says many more patients are requesting dermal fillers to repair their mouth areas after using the weight loss medication. These gel-like treatments work by injecting volume under the skin to replace lost fat and smooth out wrinkles from rapid fat loss. The treatment can restore facial fullness, eliminate lines and wrinkles, and make skin look younger again. But this fix carries a hefty price tag. Each syringe costs $700 to $2,000, depending on where you live and which doctor you see. Most people need several syringes in each treatment to achieve acceptable results.
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